A UPS plane carrying three people crashed in a massive fiery explosion shortly after taking off from Louisville’s Muhammad Ali International Airport Tuesday evening, according to officials and wild footage of its failed launch.
Shocking video shows the Hawaii-bound plane appear to lift off the runway while one of its wings was on fire before it crashes down and blows up in huge fireball.
UPS Flight 2976 exploded around 5:15 p.m. just 13 minutes after taking off, according the Federal Aviation Administration and FlightAware data.
Emergency crews are responding to an airport crash near the airport in Louisville, Kentucky on November 4, 2025.WLKY
The Louisville Metro Police Department issued a shelter-in-place order within the hour “for all locations within 5 miles of the airport,” as aerial footage showed a trail of fire and destruction behind the wrecked aircraft with a towering plume of smoke rising above.
The department later extended the order to all areas north of the airport to the Ohio River.
Multiple injuries were reported and the flames were still raging hours later as emergency personnel swarmed the scene, according to local officials.
It’s unclear at the moment the exact extent of injuries or how many passengers were on board the aircraft.WLKY
The airport was completely shuttered following the crash and the FAA and the National Transportation Safety Board are investigating.
“UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky,” the FAA said in a statement to The Post. “The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate. The NTSB will lead the investigation and will provide all updates.”
UPS confirmed its aircraft crashed and said three crew members were onboard.
The MD-11 has limited seats when used for cargo transport and can carry up to 187,393 pounds, according to Boeing, which took over manufacturing the aircraft after it merged with McDonnell Douglas in 1997.
The plane was carrying roughly 280,000 pounds of fuel, according to Louisville Mayor Craig Greenberg.
UPS confirmed that the plane involved in the crash was one of theirs.Björn Wylezich – stock.adobe.com
“There are multiple injuries and the fire is still burning. There are many road closures in the area – please avoid the scene,” Greenberg said on X.
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